Do vardenafil and tadalafil have advantages over sildenafil in the treatment of erectile dysfunction?
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چکیده
منابع مشابه
Tadalafil in the treatment of erectile dysfunction
The treatment for erectile dysfunction (ED) was revolutionized with the development of phosphodiesterase type 5 (PDE5) inhibitors. Tadalafil (Cialis((R)); Eli Lilly and Company, Indianapolis, IN, USA) is the newest and most versatile PDE5 inhibitor in the clinical armamentarium for the treatment of ED. Its most unique characteristic is its long half-life of 17.5 hours, which lends itself to a l...
متن کاملPatient preference and satisfaction in erectile dysfunction therapy: a comparison of the three phosphodiesterase-5 inhibitors sildenafil, vardenafil and tadalafil
Erectile dysfunction (ED) is a problem that may affect up to 52% of men between the ages of 40 and 70. It can be distressing because of its negative effect on self-esteem, quality of life, and interpersonal relationships. Oral phosphodiesterase-5 inhibitors (PDE5 inhibitors) are now the first choice of treatment in ED. The availability of three (sildenafil citrate, tadalafil, and vardenafil) we...
متن کاملVardenafil – A new and effective treatment for erectile dysfunction
Vardenafil (Levitra, Bayer Healthcare/GlaxoSmithKline, USA) is a phosphodiesterase 5 inhibitor developed specifically for use as an oral therapy for erectile dysfunction (ED). This review provides an overview of recent clinical trial results that support the use of this compound as first-line therapy in patients with ED. Specifically, data from clinical trials performed in multiple countries ha...
متن کاملErectile dysfunction: comparison of efficacy and side effects of the PDE-5 inhibitors sildenafil, vardenafil and tadalafil--review of the literature.
Since introduction of the PDE-5 inhibitor sildenafil 4 years ago, there has been a fundamental change in the treatment of erectile dysfunction (ED). Intracavernosal or intraurethral injections of vasoactive substances or penile implants as mechanical aids now play hardly any part in it. - The development of the PDE-5 inhibitors vardenafil and tadalafil prompts the question of whether and how th...
متن کاملDifferential effects of the phosphodiesterase type 5 inhibitors sildenafil, vardenafil, and tadalafil in rat aorta.
Presumably, the vasorelaxant properties of phosphodiesterase type 5 (PDE5) inhibitors are similar in isolated blood vessels. We aimed to explore the mechanisms underlying the vasorelaxation induced by the selective PDE5 inhibitors sildenafil, vardenafil, and tadalafil in the rat aorta. Aortic rings were mounted in 5-ml organ baths, and concentration-response curves for PDE5 inhibitors (0.0001-1...
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ژورنال
عنوان ژورنال: International Journal of Impotence Research
سال: 2006
ISSN: 0955-9930,1476-5489
DOI: 10.1038/sj.ijir.3901525